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Your Yourlocation: Home > Evaluation of tiotropium bromide(136310-93-5) in chronic obstructive pulmonary disease in a four - year clinical trial

To further observe the long-term effect of tiotropium bromide(136310-93-5) on COPD.

Methods: A randomized, double-blind test was conducted to compare the efficacy of tiotropium bromide(136310-93-5) in the treatment of patients with COPD for a period of four years, allowing patients to use any commonly used medications other than inhalation of anticholinergic drugs over a four-year period. And FEV1 /FVC accounted for the predicted value of ≤ 70%. The primary end point was the average rate of decline in FEV1 before and after the use of bronchodilator at 30 days. Including changes in FVC measurements, changes in the results of the St. George Respiratory Questionnaire (SGRQ), acute exacerbation of COPD, and mortality.

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