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Your Yourlocation: Home > Observation on Curative Effect of Inhaled Tiotropium Bromide(136310-93-5) in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

To observe the clinical efficacy of inhaled tiotropium bromide(136310-93-5) in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD).

Methods: Thirty patients with acute exacerbation of COPD were randomly divided into two groups. The control group(n = 15) was inhaled with tiotropium bromide(136310-93-5). The control group(n = 15) was inhaled with ipratropium bromide aerosol. FEV1 and 1 s forced expiratory volume (FEV1) /forced expiratory volume(FVC) at 10 days after treatment.

Results: The clinical symptoms of the treatment group were better than those of the control group(P <0.05). FEV1 accounted for FEV1% and FEV1 /forced expiratory volume (FVC) significantly increased compared with the control group(P <0.01).

Conclusion: Inhalation of tiotropium bromide(136310-93-5) can significantly improve the symptoms and improve FEV1%, FEV1 /FVC, and no serious adverse drug reactions in the treatment of acute exacerbation of CDPD.

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