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Your Yourlocation: Home > Efficacy of tiotropium bromide(136310-93-5) in the treatment of 41 patients with chronic obstructive pulmonary disease

Objective: To investigate the clinical efficacy and safety of tiotropium bromide(136310-93-5) in the treatment of chronic obstructive pulmonary disease.

Methods: 82 patients with chronic obstructive pulmonary disease were divided into control group and observation group, 41 cases in each group. The control group was treated with ipratropium bromide aerosol. The observation group was treated with tiotropium bromide powder. The clinical efficacy and adverse events were compared between the two groups.

Results: After treatment, the improvement rate of clinical symptoms and signs was 92.68% in the observation group, which was significantly higher than that in the control group(P <0.05). Meanwhile, the FEV1, FVC and FEV1(P <0.05), and the incidence of adverse reactions in the two groups was similar, and the difference was not statistically significant(P> 0.05).

Conclusion: Tiotropium bromide(136310-93-5) powder treatment of patients with chronic obstructive pulmonary disease has a very significant therapeutic effect, its efficacy lasting, safe and reliable, worthy of clinical application.

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