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Your Yourlocation: Home > Efficacy of tiotropium bromide(136310-93-5) combined with high-dose salmeterol /ticecathone in the treatment of moderate to severe chronic obstructive pulmonary disease

To investigate the clinical efficacy of tiotropium bromide(136310-93-5) combined with high-dose salmeterol / ticecathone in the treatment of patients with stable moderate to severe chronic obstructive pulmonary disease. Methods: The clinical data of 60 patients with moderate to severe chronic obstructive pulmonary disease were retrospectively analyzed. The patients were randomly divided into two groups (n = 30). The rats in the observation group were treated with tiotropium bromide(136310-93-5) combined with high-dose salmeterol / ticyclofen, and the control group was treated with high-dose salmeterol / ticyclofen. The clinical efficacy of the two groups was compared. Results: In the observation group, 25 patients were treated and 4 cases were effective. The total effective rate was 96.7%. In the control group, 18 patients were treated and 6 patients were effective. The total effective rate was 80.0%. The total effective rate of the observation group was significantly higher than the control group, the difference was statistically significant (P <0.05). The pulmonary function of the observation group was improved, which was significantly better than that of the control group, the difference was statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 6.7%; the incidence of adverse reactions in the control group was 23.3%. The incidence of adverse reactions in the observation group was significantly lower than that in the control group, the difference was statistically significant (P <0.05). Conclusion: Tiotropium bromide(136310-93-5) combined with high dose salmeterol /ticlocaine has a good clinical effect in the treatment of moderate to severe chronic obstructive pulmonary disease and deserves clinical promotion.

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