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Your Yourlocation: Home > Treatment of 53 cases of AECOPD with salbutamol sulfate combined with tiotropium bromide(136310-93-5)

To investigate the clinical efficacy of salbutamol sulfate combined with tiotropium bromide(136310-93-5) in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: Forty - nine patients were randomly divided into control group (n = 46) and observation group (n = 53). In addition to conventional therapy, the control group was given inhalation of tiotropium 18μg and pumicetole 1mg, 2 times a day; observation group on the basis of the control group was given inhaled salbutamol sulfate 2mL, 2 times a day for 10 days. Before and after treatment, lung function, blood gas analysis index, statistical efficacy and St. George Respiratory Disease Questionnaire (SGRQ) quality of life score were measured. Results: The total effective rate was 90.6% in the observation group and 76.1% in the control group. The observation group was higher than the control group (χ2 = 3.81, P <0.05). After treatment, the lung function indexes of the two groups were increased (P <0.05). The scores of SGRQ in the two groups were significantly lower than those in the control group (P <0.05). The blood gas index of the observation group was significantly decreased (P <0.05). Conclusion: Salbutamol sulfate combined with tiotropium bromide(136310-93-5) in the treatment of AECOPD significantly, can significantly improve lung function and blood gas indicators, less adverse reactions, worthy of clinical promotion.

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