NewsEvents

Your Yourlocation: Home > Clinical observation of different doses of tiotropium bromide(136310-93-5) inhalation in the treatment of chronic obstructive pulmonary disease

To observe the clinical efficacy of different doses of tiotropium bromide(136310-93-5) inhalation in patients with chronic obstructive pulmonary disease (COPD). Methods: Forty-one patients with COPD were randomly divided into two groups: routine treatment group (n = 46), male group (n = 46), age group (61.7 ± 9.3) years old, 18 μg tiotropium bromide observation group (n = 45 (63.4 ± 8.5) years old; 32μg tiotropium bromide observation group (n = 43), male 39, female 4, age (63.2 ± 9.0) years old, 3 groups were given. The same conventional treatment, 18μg tiotropium bromide observation group given 18μg /day tiotropium bromide, 32μg tiotropium bromide observation group given 32μg /day tiotropium bromide(136310-93-5). Treatment for 12 weeks, at the beginning of treatment 1d, 1w, 4w, 8w, 12w and other different observation time points to observe the degree of improvement of lung function and dyspnea. Results: After treatment, the lung function and dyspnea of the three groups were improved to some extent before treatment. However, compared with the conventional treatment group, the St. George's Respiratory Questionnaire (SGRQ) and the transition dyspnea index (TDI) were significantly better than those in the control group (P <0.05 ), the first expiratory volume in one second (FEV 1) was significantly improved compared with that before treatment (P <0.05), 32μg tiotropium bromide observation group improved more significantly, with 18μg tiotropium bromide observation. The difference was significant (P <0.05). Conclusion: Tiotropium bromide(136310-93-5) can alleviate the difficulty of breathing and expand the symptoms of COPD patients by expanding the bronchus. And the dosage was 32μg / d, the effect was better than 18μg /d.

Address: TEL:0531-82375879 Tiotropium Bromide
© Copyright(C)2014 JINAN DEXINJIA BIO & TECH CO., LTD All Rights Reserved