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Your Yourlocation: Home > Effect of tiotropium bromide(136310-93-5) combined with salmeterol inhalation on moderate to severe COPD in patients

To study the clinical efficacy of tiotropium bromide(136310-93-5) combined with salmeterol inhalation in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Methods: Ninety patients with moderate to severe COPD were randomly divided into observation group and control group (n = 45). The patients in the control group were treated with conventional cough and phlegm, anti-infection and oxygen. The observation group was treated with tiotropium bromide(136310-93-5) and salmeterol inhalation on the basis of routine treatment. The arterial blood before and after treatment was measured Oxygen partial pressure (PaO2) level, carbon dioxide partial pressure (Pa CO2) level, 1 second forced expiratory volume (FEV1), and FEV1 as a percentage of predicted value (FEV%). Results: The blood gas analysis was improved in both groups after treatment, and the improvement was more significant in the observation group (P <0.05). In the control group, the effect of lung function was improved significantly (P <0.05), the observation group improved significantly (P <0.05). Conclusion: Tiotropium bromide(136310-93-5) combined with salmeterol inhalation in the treatment of moderate to severe COPD patients, can effectively improve lung function, improve blood pressure, help patients to early recovery, worthy of application.

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