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Your Yourlocation: Home > Efficacy of tiotropium bromide(136310-93-5) and sulindil in the treatment of moderate to severe chronic obstructive pulmonary disease

To investigate the efficacy of tiotropium bromide(136310-93-5) and sulpiride in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Methods: Fifty patients with moderate to severe COPD were divided into observation group and control group according to different treatment methods. The observation group was treated with tiotropium bromide(136310-93-5) and sulindril combination. The control group was treated with sulindi, Pulmonary function and 6 min walking test (6MWD) and dyspnea scale (MMRC) scores were compared between the two groups. Results: The predicted values of FEV1, FEVC / FCV (%) and FEV1% were significantly higher in the observation group than those in the control group at 3 months after treatment. The difference was statistically significant (P <0.05). The scores of MMRC and 6MWT in the observation group were also higher than those in the control group (P <0.05). Conclusion: The combination of tiotropium and sulbide in the treatment of COPD is superior to that of monotherapy. It is worthy to be popularized.

To observe the therapeutic effect of salmeterol / propofolone propionate combined with tiotropium bromide(136310-93-5) inhalation on remission of chronic obstructive pulmonary disease (COPD). Methods: Randomized, double- 85 patients with COPD were divided into observation group and control group. Group A was treated with tiotropium bromide(136310-93-5) and salmeterol / propofenone propionate group. Group B was treated with salmeterol / valprofenate in group B, (6MWD) were compared between the two groups.Results: After 3 months of treatment, compared with the control group, the pulmonary function indexes FEV1, FEV1 / FVC% (P <0.05). Conclusion: Tiotropium bromide combined with salmeterol / propafenone propofol inhalation is effective in the treatment of COPD, and the curative effect is better than that of salmeterol.

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