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Your Yourlocation: Home > Effect of tiotropium bromide(136310-93-5) combined with sulpiride on stable stage of chronic obstructive pulmonary disease

To evaluate the efficacy of inhaled tiotropium bromide(136310-93-5) combined with sulpiride in the treatment of patients with stable chronic obstructive pulmonary disease (COPD). Methods: Sixty patients with stable COPD Ⅱ-Ⅲ stable phase were randomly divided into tiotropium group, (P <0.05) .There was no significant difference between the two groups (P> 0.05). Conclusion: Tiotropium bromide is the most important factor in the treatment of COPD patients after treatment, ammonium combined with sulpiride has a better therapeutic effect on lung function in patients with stable COPD.

To investigate the efficacy of tiotropium bromide(136310-93-5) combined with low-flow oxygen in the treatment of chronic obstructive pulmonary disease (COPD) with stable respiratory failure. Methods: 72 patients with COPD stable respiratory failure were randomly divided into two groups. The combined treatment group was given tiotropium combined with low flow oxygen therapy (2 L /min). The control group was treated with low-flow oxygen (2 L / min), and the lung function was observed before and after treatment for 3 months. The exercise ability (6 MWD /m) and the quality of life score (SGRQ). Results: After 3 months of treatment, the pulmonary function indexes (FVC, FEV1 and FEV1 / FVC%) were improved in all patients. The 6-minute walk distance evaluation exercise ability and quality of life score were improved, but the improvement of the combined treatment group , Compared with the control group, the difference was statistically significant (P <0.05). Conclusion: Long-term anticholinergic tiotropium bromide(136310-93-5) combined with low-flow oxygen therapy can significantly improve the dyspnea and pulmonary function in COPD patients, which is superior to simple low-flow oxygen therapy.

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