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Your Yourlocation: Home > Efficacy of injection combined with tiotropium bromide(136310-93-5) in the treatment of chronic obstructive pulmonary disease

To investigate the clinical efficacy of Shenmai injection combined with tiotropium bromide(136310-93-5) in the treatment of chronic obstructive pulmonary disease. Methods: Sixty - eight patients with chronic obstructive pulmonary disease (COPD) admitted to Xuanwu Hospital of Capital Medical University from July 2014 to March 2015 were randomly divided into control group (31 cases) and treatment group (37 cases). The control group was inhaled tiotropium powder, 18μg / time, once / d. The treatment group was injected intravenously with Shenmai injection on the basis of the control group, 100 mL / time, 1 time / d. Two groups of patients were treated continuously for 14 days. The clinical efficacy of the two groups was observed, and the arterial blood gas index, pulmonary function index and recurrence were compared between the two groups. Results: After treatment, the total effective rate of the control group and the treatment group were 74.19%, 91.89%, the difference between the two groups was statistically significant (P <0.05). After treatment, the blood oxygen partial pressure (pO2) and oxygen saturation (SpO2) were significantly increased, while the partial pressure of carbon dioxide (pCO2) decreased significantly, the difference was statistically significant (P <0.05) (P <0.05). The improvement of these observation indexes in the treatment group was significantly better than that in the control group. The difference between the two groups was statistically significant (P <0.05). (FEV1), forced vital capacity (FVC) and FEV1 / FVC were significantly higher in the two groups (P <0.05), and the difference between the two groups was statistically significant (P <0.05) .Conclusion: The level of the index is significantly higher than that of the control group (P <0.05). The relapse rates of the control group and the treatment group were 38.71% and 10.81% respectively. There was significant difference between the two groups (P <0.05). Conclusion: Shenmai injection combined with tiotropium bromide(136310-93-5) in the treatment of chronic obstructive pulmonary disease has a good clinical effect, can significantly improve lung function, safety, and has a certain clinical application value.

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