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Your Yourlocation: Home > Effect of tiotropium bromide(136310-93-5) and budesonide combined with inhalation on chronic obstructive pulmonary disease

To compare the efficacy of inhaled tiotropium alone and inhaled budesonide alone in chronic obsequious pulmonary diseases (COPD). Methods: A total of 100 COPD patients were randomly divided into A and B groups. Group A was inhaled tiotropium bromide(136310-93-5) 18μg / d; group B was inhaled tiotropium bromide 18μg / d, plus budesonide 200μg, 2 times / d, the whole trial for 6 weeks. FEV1, FVC, St. Louis Respiratory Questionnaire (SGRQ), 6 min walking distance (6 MWT) were measured before and after the start of the trial, and emergency drug use was urgently used. Results: 81 cases were completed. After treatment, SGRQ and 6MWT were significantly improved in group B (P <0.05). FEV1, FVC and emergency remission were similar to those of group A. CONCLUSION: Inhalation with budesonide improves the health-related quality of life (HRLQ) compared with inhaled tiotropium alone. The data suggest that the addition of low-dose budesonide enhances the efficacy of tiotropium.

To study the therapeutic effect of inhaled tiotropium in the treatment of stable chronic obstructive pulmonary disease (COPD). Methods: From October 2008 to January 2009, 50 patients with stage Ⅱ and Ⅱ COPD were randomly divided into treatment group and control group. The treatment group received tiotropium bromide(136310-93-5) powder (18ug, day 1), the control group received theophylline sustained-release tablets, each 0.1, 2 times a day, treatment for 12 weeks. The patients were followed up for 4 weeks, 6 weeks, 10 weeks and 12 weeks. The lung function and blood gas analysis were measured before and 6 weeks and 12 weeks after treatment. Patients aged 35 to 70 years, in line with the 2007 Chinese Medical Association Respiratory Medicine Branch to develop diagnostic criteria, excluding bronchial asthma, bronchiectasis, congestive heart failure, tuberculosis, 2 weeks before the test with systemic infection, severe heart, liver Kidney, blood system.

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