NewsEvents

Your Yourlocation: Home > Effects of Tiotropium Bromide(136310-93-5) Supplementation on Oxygenation and Inflammatory Reaction in COPD Patients with Type Ⅱ Respiratory Failure

To investigate the effect of tiotropium bromide(136310-93-5) adjuvant therapy on the oxygenation function and inflammatory response in patients with chronic obstructive pulmonary disease (COPD) complicated with type Ⅱ respiratory failure. Methods: COPD combined with COPD from August 2012 to January 2016 was collected. 58 patients were randomly divided into observation group (n = 29) and control group (n = 29) according to the single-blind randomized control group.The control group received routine clinical treatment, and the observation group was treated with tiotropium bromide. The levels of serum inflammatory cytokines were measured by enzyme-linked immunosorbent assay (ELISA). The levels of serum inflammatory cytokines were measured by enzyme-linked immunosorbent assay (ELISA) before and after treatment, and the pulmonary function was measured by lung function instrument at 30 days after treatment. (P <0.05). After 30 days of treatment, the first-second forced expiratory volume (FEV1) and 75% of the vital capacity were significantly higher in the two groups (P> 0.05). There was no significant difference in the pulmonary function, (PEF), oxygenation index (PaO 2 / FiO 2), oxygen delivery (DO 2) and oxygen uptake rate (O 2 ER) were significantly higher than those in the control group, the level of oxygen consumption (VO2) was significantly lower than that of the control group (P <0.05) (IL-1), interleukin-18 (IL-18), interleukin-27 (IL-27) and C-reactive protein (CRP) were significantly lower than those in the control group (P <0.05) tiotropium bromide(136310-93-5) adjuvant therapy can optimize COPD patients with type Ⅱ respiratory failure in patients with pulmonary ventilation and oxygenation function, reduce the degree of systemic inflammatory response.

To observe the efficacy of docosylidene tablets combined with the taste of Australian powder according to the treatment of coal workers pneumoconiosis. Methods: The patients were randomly divided into observation group and control group. The rats in the observation group were treated with Doxofloxacin, and the control group was treated with polysenoylate tablets. The therapeutic effect was compared between the two groups. Results: The total effective rate of the observation group was significantly higher than the control group, the difference was statistically significant (P <0.05). The improvement of lung function in the observation group was better than that in the control group, the difference was statistically significant (P <0.05). Conclusion: Doxofylline tablets combined with the taste of Australia by powder aerosol treatment of coal workers have a good effect, can effectively improve the patient's respiratory function.

Address:211#Zhengfeng Building,Huanbaokejiyuan, Gaoxinkaifaqu, Jinan,250100,China TEL:086-531-82375818 Tiotropium Bromide
© Copyright(C)2014 JINAN DEXINJIA BIO & TECH CO., LTD All Rights Reserved