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A study showed that pulmonary function prompted ACOS patients with ICS treatment after FEV1 was significantly increased, sputum eosinophil count, chest HRCT on the improvement of BWT and FEV1 have a correlation, suggesting that ICS is the method of treatment of ACOS, sputum Granulocyte count, BWT can predict the reactivity of ICS therapy. Louie and other studies have shown that patients with severe AC in patients with ACOS response to treatment with omeprazole monoclonal antibody can reduce the number of acute exacerbations and the use of hormones, recommended oxamine monoclonal antibody associated with increased blood IgE (30 ~ 700IU / ML) and age ≥ 12 years old ACOS patients, treatment for 4 to 6 months, but before the need to use tiotropium bromide(136310-93-5), roxofloxacin and other drug control symptoms.

Bronchial asthma and chronic obstructive pulmonary disease (COPD) are considered two different diseases, but both have common clinical manifestations. The current guidelines for asthma treatment and chronic obstructive pulmonary disease strategies /guidelines refer to both clinical coexistence states, but their definitions and treatments are not elaborated. Studies have shown that asthma and chronic obstructive pulmonary disease in the risk factors, inflammatory characteristics, clinical features and other aspects of overlap, some scholars will be temporarily defined as "bronchial asthma - chronic obstructive pulmonary syndrome (asthma-complex syndrome).

ACOS is an airway inflammatory disease that participates with inflammatory mediators such as neutrophils, eosinophils, and IL-4. There is a lack of clear diagnostic criteria and treatment guidelines, based on the characteristics of pathophysiology, reference to asthma guidelines, chronic obstructive pulmonary disease and the patient's own characteristics, to take individual diagnosis and comprehensive treatment, may provide more meaningful clinical and research guidance.

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