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Your Yourlocation: Home > Tiotropium bromide(136310-93-5) is one of the long-acting anticholinergic drugs

Inhalation of anticholinergic drugs: short-acting such as ipratropium bromide, long-acting such as tiotropium bromide(136310-93-5) and so on. Can block postganglionic vagal nerve branch, reduce the vagus nerve tension and diastolic bronchial. The role of expansion of the bronchial than the β2 receptor agonist weak, slow onset, long and difficult to produce drug resistance, the elderly good effect.

Bronchial asthma is an airway chronic inflammatory disorder involving multiple cells (eg, eosinophils, mast cells, T lymphocytes, neutrophils, airway epithelial cells, etc.) and cellular components. This chronic inflammation leads to increased airway hyperresponsiveness and causes recurrent wheezing, shortness of breath, chest tightness or coughing symptoms, often at night and /or early morning attacks, exacerbated, often appear wide and varied reversible airflow limited, the majority of patients can be self-mitigation or treatment by the remission.

Complications of bronchial asthma:

Pneumothorax, mediastinal emphysema, atelectasis, chronic bronchitis, pulmonary emphysema, bronchiectasis, interstitial pneumonia, pulmonary fibrosis and pulmonary heart disease.

Treatment goal:

(1) Effective control of acute attack symptoms and maintain the lightest symptoms, even without any symptoms

(2) To prevent asthma aggravated

(3) Keep lung function as close as possible to normal levels

(4) The ability to maintain normal activities (including exercise)

(5) To avoid the adverse reactions of asthma drugs

(6) To prevent irreversible airflow limitation

(7) To prevent asthma death, reduce asthma mortality

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