Your Yourlocation: Home > Tiotropium bromide(136310-93-5) is one of the commonly used anticholinergic drugs

Commonly used anticholinergic drugs are: ipratropium bromide, tiotropium bromide(136310-93-5), etc., for the cholinergic receptor blockers, by inhibiting the acetylcholine receptor, blocking the posterior vagal nerve pathway, reduce vagal excitability and diastolic bronchial smooth muscle, but also reduce glandular secretion. A new generation of anticholinergic drugs (such as tiotropium bromide(136310-93-5)) and β2 agonists have a synergistic effect, can significantly enhance the bronchial diastolic effect, especially for severe asthma and nocturnal asthma, can significantly improve symptoms and sleep oxygenation, improve lung gas distribution, reduce the number of acute attacks.

Bronchial asthma is a serious respiratory disease, and also an immune dysfunction abnormal allergic disease, is a worldwide problem, it has high incidence, long duration and repeated attacks, has become a serious public hygiene issue. The disease is currently no radical cure, but can use drugs to ease, if the treatment is not timely or inappropriate, most likely endanger the lives of patients, seriously affecting their physical and mental health, also bring a huge financial burden to the family and society.

Drugs for the treatment of asthma can be divided into controlled drugs and relieving drugs. ① Control drugs: the use of anti-inflammatory effects of asthma control, the need for long-term use of drugs are mainly anti-IgE receptor agonists, sodium cromoglycans, sustained release theophylline, long-acting β2 receptor agonists, leukotriene regulation agent, inhaled glucocorticoid (GCS) and so on. ② Relieve drugs: rapid lifting of bronchial spasm, so as to relieve the onset of asthma, according to the need to apply drugs, the main drugs are short-acting β2 receptor agonists, short-acting theophylline, inhaled anticholinergic drugs, systemic use of hormones and quick inhalation Β2 receptor agonists and so on.

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