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For adults older than 18 years of age, tiotropium bromide(136310-93-5) can be used as an additional treatment option for treatment if there is an acute exacerbation of asthma. Previous reports have described it as a treatment for severe asthma.

Primary medical units should be given inhalation of SABA + ipratropium bromide in combination with hormones (oral or intravenous) and, if possible, controlled oxygen at the same time, in the preparation of trans-treatment. The 2014GINA report only mentioned the use of SABA, hormones, controlled oxygen therapy, did not mention ipratropium bromide.

In view of the frequent occurrence of respiratory infections in preschool children, the current use of short-term oral hormones or inhalation of high-dose hormones in the treatment of acute exacerbation or wheezing in preschool children is not routinely due to the potential long-term systemic adverse effects of hormones, especially when used frequently.

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