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Your Yourlocation: Home > Progress in treatment of senile chronic obstructive pulmonary disease (COPD) with tiotropium bromide(136310-93-5)

This is the main measure to alleviate COPD symptoms. And asthma treatment is similar to the preferred method of inhalation can be applied short or long-acting β2 receptor agonists, anticholinergic drugs or theophylline, combined with the above mechanism of action different drugs can improve efficacy and reduce adverse reactions. Anticholinergic new tiotropium bromide(136310-93-5) selectively act on the parasympathetic M1, M3 receptor, long-acting, inhalation once daily, can significantly improve the nighttime symptoms and sleep oxygenation, improve lung gas distribution, reduce the number of acute attack, and salmeterol or formoterol combined with a significant synergistic effect.

At present, COPD patients with long-term inhalation corticosteroid-dose relationship and safety is not clear, is the global multi-center clinical trials. The available data suggest that long-term inhaled corticosteroids do not prevent a one-second forced expiratory volume (FEV1) from falling, and are only applicable to patients with symptomatic and improved lung function after symptomatic inhalation therapy or increased airway responsiveness. Acute exacerbation can be short-term (10 to 15 days) systemic corticosteroids, long-term use in addition to the well-known side effects, steroid myopathy can increase respiratory muscle fatigue and muscle atrophy.

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