Your Yourlocation: Home > Salmeterol in combination with tiotropium bromide(136310-93-5) can improve lung function

Tiotropium bromide(136310-93-5) is a derivative of ipratropium bromide, its affinity for M1, M2, M3 receptors is similar, but tiotropium and M1 and M3 receptor dissociation rate is 100 times slow than ipratropium bromide ammonium, M1 and M3 receptor slow dissociation of tiotropium bromide(136310-93-5) has long-term characteristics of clinical COPD patients with a strong and lasting bronchial dilatation and protection, while tiotropium also has anti- inflammation of the role, it keeps the airway open 24 hours to avoid repeated airway collapse and opening and airway tissue friction, which itself can prevent the occurrence of airway inflammatory response; long-term inhalation can increase the amount of deep breathing, pneumonic lung volume, thereby improving breathing difficulties, improve exercise tolerance and quality of life, but also reduce the frequency of acute exacerbations.

According to the "Guidelines", the department of lung function Ⅲ, Ⅳ grade COPD patients were regularly inhaled salmeterol teasone, part of the economic situation of patients at the same time combined with tiotropium bromide inhalation agent. This study shows that the inhalation of salmeterol in patients with pulmonary function improved significantly, and combined with tiotropium bromide(136310-93-5) in patients with lung

function than before treatment to improve the number of acute exacerbation than the single use of salmeterol inhalation agent reduced. COPD patients due to repeated hospitalization, most of the economic difficulties, because the two drugs combined with the monthly cost of 800 to 1,000 yuan, for most patients simply unable to afford. Through the study of the authors believe that although the two drugs with a higher monthly cost, but more than the cost of hospitalization can still save a lot of savings, the most important is the combination of two drugs to help improve the quality of life of patients, improve lung function, so for conditional severe and very severe COPD patients can still consider the combination of two drugs.

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