Your Yourlocation: Home > Treatment of Cough Variant Asthma with Tiotropium Bromide(136310-93-5) and Capsule

Cough variant asthma in the clinical main features of intractable, irritating cough, easy to attack after exposure to allergens, and patients with cough symptoms will be repeated and persistent, lasted more than 1 month, the patient in the morning and no obvious symptoms of night attacks, and less sputum, mostly irritating cough, increased symptoms after exercise, if not treated, it is easy to develop into a true sense of bronchial asthma, seriously affecting the quality of life of patients, and even life-threatening. Tiotropium bromide(136310-93-5) is a bronchodilator, it can bronchial smooth muscle relaxation, to some extent alleviate bronchial spasm, effectively inhibit bronchial secretions increased, significantly improved breathing difficulties. 

WISDOM study confirmed that bronchodilator is the cornerstone of the treatment of chronic obstructive pulmonary disease, tiotropium bromide(136310-93-5) and salmeterol treatment of patients with severe chronic obstructive pulmonary disease, the gradual cessation of glucocorticoid does not increase in patients with severe COPD acute lung increase the risk.

The new GOLD guidelines compare the efficacy profile of anticholinergic drugs: the long-acting anticholinergic is effective for at least 12 hours and the duration of tiotropium bromide(136310-93-5) and glycopyrrolate is up to 24 hours or more. Tiotropium has been shown to reduce acute exacerbations and associated hospitalizations, improve symptoms and health status (category A), and improve the effectiveness of pulmonary rehabilitation (type B evidence). A large study confirms that tiotropium reduces acute exacerbations better than salmeterol, a long-acting beta2 agonist. The role of atenolide and glycopyrrolate in pulmonary function and dyspnea is similar to that of tiotropium, with little evidence in other respects.

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