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Your Yourlocation: Home > Efficacy of combination of tiotropium bromide(136310-93-5) and seretide in patients with stable COPD

To observe the effect of tiotropium bromide(136310-93-5) combined with seretide on pulmonary function and quality of life in patients with stable chronic obstructive pulmonary disease (COPD). Studies have shown that combination therapy with tiotropium and sulindac improves lung function and improves quality of life in stable COPD, and should be widely used clinically. The article published on the "China Practical Medicine".

70 patients with stable COPD were randomly divided into observation group (35 cases) and control group (35 cases). The control group was only inhaled Seretide (Salmeterol / Fluticasone) 50 / 250μg, 2 times / The combination of tiotropium bromide(136310-93-5) and seretide was given to the patients inhalation of sildenide 50 / 250μg, 2 times / d, inhalation of tiotropium bromide(136310-93-5) 18μg, once a day, and lung function monitoring instrument before and after treatment (FEV1, forced vital capacity FVC, deep inspiratory capacity IC) were used to evaluate the quality of life of the patients by using the St. George Respiratory Questionnaire (SGRQ).

The FEV1, FVC, IC of the two groups were significantly higher than those before treatment (P <0.05), and the scores of SGRQ were significantly lower than those before treatment (P <0.05) (P <0.05), SGRQ score was significantly lower than the control group (P <0.05).

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