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Your Yourlocation: Home > Clinical observation of tiotropium bromide(136310-93-5) combined with noninvasive ventilation in treatment of 68 patients with COPD Ⅱ respiratory failure

Tiotropium combined with noninvasive ventilation in the treatment of COPD Ⅱ respiratory failure in 68 cases, the study found that tiotropium bromide(136310-93-5) combined with non-invasive ventilation can effectively improve the patients with chronic obstructive pulmonary disease with type Ⅱ respiratory failure in patients with blood gas, is worthy of clinical application. The article published on 2014, 25 issue of "Chinese Medicine Guide".

The aim of this study was to investigate the efficacy of tiotropium bromide(136310-93-5) plus noninvasive ventilation in the treatment of chronic obstructive pulmonary disease (COPD) with type II respiratory failure.

METHODS: Sixty-eight patients with chronic obstructive pulmonary disease (COPD) and type II respiratory failure were randomly assigned to control and treatment groups. The patients in the treatment group were treated with tiotropium bromide(136310-93-5) powder inhalation (Si Lihua). The treatment group was given oxygen therapy, anti-infection, expectorant, bronchodilator and other non-invasive ventilation treatment. The changes of arterial blood gas before and after treatment were compared between FEV1% (FEV1%) and dyspnea score (MMRC).

The results showed that the arterial blood gas, FEV1%, MMRC of the two groups were significantly improved after treatment, and there was significant difference between the two groups (P <0.05).

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