Your Yourlocation: Home > Efficacy of combined inhaled tiotropium bromide(136310-93-5) and salmeterol /fluticasone in the treatment of chronic obstructive pulmonary disease

To investigate the clinical efficacy of tiotropium bromide(136310-93-5) powder inhalation combined with methotrexate / fluticasone in the treatment of chronic obstructive pulmonary disease (COPD). The combination of tiotropium bromide(136310-93-5) and salmeterol / fluticasone has been shown to improve clinical symptoms and signs in patients with COPD, promote recovery of lung function, reduce the impact on life and reduce the number of acute exacerbations, with significant efficacy and safety , Can be used as the first choice for clinical treatment of COPD. This article was published on issue 03, 2015, Journal of Clinical and Experimental Medicine.

Methods: One hundred and fifty patients with COPD underwent aerosol inhalation therapy from June 2011 to June 2013 using a prospective parallel trial. The patients were divided into two groups with 75 randomly selected groups. The control group received aerosol inhalation of salmeterol for the inhalation of powder (inhalation of 50μg salmeterol /250μg of fluticasone propionate), the experimental group inhalation of salmeterol inhaled ticerone inhalation powder + tiotropium bromide(136310-93-5) powder inhalant. The lung function, clinical symptoms, clinical curative effect and prognosis of the two groups were compared and analyzed.

After treatment, the improvement of lung function in experimental group was better than that in control group (P <0.05), the improvement of clinical symptoms was better than that of the control group (P <0.05), the physical condition of the patients The total effective rate of treatment was significantly higher than that of the control group (P <0.05). No serious adverse reaction occurred. The acute attack rate of the experimental group was lower than that of the control group (P <0.05).

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