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Your Yourlocation: Home > Effects of tiotropium bromide(136310-93-5) on inflammatory factors and pulmonary function in stable COPD patients

To investigate the effect of tiotropium bromide(136310-93-5) on serum levels of inflammatory cytokines and pulmonary function in patients with stable chronic obstructive pulmonary disease (COPD). Studies have shown that the use of tiotropium bromide(136310-93-5) powder inhalation in the treatment of patients with stable COPD, can correct the abnormal expression of serum inflammatory cytokines, and significantly improve the patient's lung function. The article published on "Journal of Clinical and Experimental Medicine".

100 cases of stable COPD patients were randomly divided into observation group and control group, each group of 50 cases. Patients in the control group were treated with oral theophylline sustained-release tablets, and patients in the observation group were treated with tiotropium bromide(136310-93-5) dry powder inhalation. Serum levels of hs-CRP and TNF-α were determined before and after treatment.

Serum inflammatory cytokine levels and lung function indexes of the two groups were significantly improved compared with those before treatment, and the above indexes of the observation group were better than those of the control group.

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