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Your Yourlocation: Home > Clinical observation of tiotropium bromide(136310-93-5) combined with Budesonide Formoterol powder in maintenance treatment

Zhangjiagang Jin Gangzhen People's Hospital, a Division of researchers published papers to observe the combination of tiotropium bromide(136310-93-5) powder and budesonide tofu powder maintenance treatment of chronic obstructive pulmonary disease (COPD) clinical efficacy. The study showed that tiotropium powder combined with budesonide formoterol powder maintenance treatment of COPD can improve lung function, improve the quality of life and motor function, reduce the incidence of acute exacerbation of COPD. The article published in the 08th issue of 2015 "Chinese Journal of Clinical Research".

136 patients with COPD from Jan. 2011 to Oct. 2014 were divided into 3 groups according to the different treatment methods. Tiotropium bromide(136310-93-5) powder combined with Budesonide Formoterol powder was used to treat Group A (N = 49) treated with budesonide formoterol powder as group B (n = 46) treated with tiotropium bromide(136310-93-5) powder as group C (n = 41). (FEV1), forced vital capacity (FVC), FEV1 / FVC, St. George's Respiratory Questionnaire (SGRQ), and 6-min walk test (6MWD) before and after enrollment. All patients were followed up for 1 year. After 1 year, these indexes of patients were examined, and the incidence of acute exacerbations was observed.

After treatment, FEV1, FVC and FEV1 / FVC were significantly improved (P <0.05, P <0.01), and FEV1, FVC and FEV1 / FVC after treatment were significantly better in group A than that of monotherapy (P <0.05, P <0.01). After treatment, SGRQ and 6MWD were significantly improved (P <0.05, P <0.01), and SGRQ and 6MWD in group A were significantly better than those in group B and C (P <0.01). The incidence of acute exacerbation was 38.8%, 56.5% and 65.9% in the A, B and C groups, respectively. There was significant difference between the two groups (P <0.01).

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