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Your Yourlocation: Home > The long-acting anticholinergic effect of tiotropium bromide(136310-93-5) continues for more than 24 hours

Long-acting anticholinergic drug tiotropium bromide(136310-93-5) efficacy lasted more than 24 hours, can reduce the acute exacerbation and related hospitalization rate, improve symptoms, and effectively enhance pulmonary rehabilitation therapy.

Compared with atropine, the ipratropium bromide, oxitropium bromide and tiotropium bromide(136310-93-5)  systemic side effects are rare, relatively large doses within the drug is relatively safe, the main side effects of dry mouth. Inhalation of 18 μg of tiotropium powder per day had no effect on mucociliary clearance. Studies have found that inhalation of ipratropium bromide can cause mouth pain and mouth metal taste. COPD patients were treated with ipratropium bromide and a small increase in cardiovascular events. Inhalation of anticholinergic drugs in the face mask can induce acute glaucoma.

According to two new trials, Boehringer Ingelheim's recently approved Spiolto, a compound drug for chronic obstructive pulmonary disease (COPD), can significantly improve patient quality of life. Spiolto is a combination of the active ingredients in Boehringer Ingelheim's long-acting muscarinic antagonist Spiriva (tiotropium bromide(136310-93-5)) and the active ingredient in the long-acting beta receptor agonist Striverdi (olodaterol), which recently The European Union and the United States (in the United States under the trade name Stiolto) approved the listing.

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